We are pleased to announce that a collaborative research project involving ABCD Lab has been selected for the 2026 A3 Foresight Program, jointly supported by the National Research Foundation of Korea (NRF), the National Natural Science Foundation of China (NSFC), and the Japan Society for the Promotion of Science (JSPS). The A3 Foresight Program supports tri-national research collaborations among leading institutions in Korea, China, and Japan to establish world-class researc

We are excited to share that our article, “Astrocytic Ankyrin-2 Enables Memory Persistence in the Mouse Hippocampus”, has been published in Nature Communications and is now available online. The Stars That Hold Our Memories Why do some memories last for weeks, months, or even years, while others quickly fade away? Astrocytes may hold the key. Memory persistence is a fundamental feature of memory, yet the cellular mechanisms that support the long-term stability of memory trace

Two years ago, Dr. Koh, together with colleagues from South Korea, participated in the "Astrocytes in Brain Function and Disease Symposium" held at the Nobel Forum at Karolinska Institutet in Sweden, a venue well known for hosting scientific discussions associated with the Nobel Prize community. At the symposium, leading brain scientists and clinicians gathered to discuss emerging therapeutic strategies targeting astrocytes in brain disorders. Based on these discussions and c

We are excited to share that our article, “Deep Learning with Zero Initialization: Revisiting Symmetry Breaking and Gradient Flow” has been published in Neural Processing Letters (Nature Portfolio) and is now available online. In this work, we revisit a long-standing assumption in deep learning that zero initialization prevents effective learning due to symmetry issues. We show that this is not necessarily the case. Under certain conditions, neural networks can still learn ef

On July 24, 2025, our perspective article, "Potential role of astrocyte on gamma-aminobutyric acid tone regulation during developmental period," was published in Neural Regeneration Research (IF: 6.7) and is now available online. In this work, we discuss how astrocytes may regulate GABA tone during early brain development. While GABA is usually known as an inhibitory neurotransmitter in the adult brain, it actually has excitatory effects during development, influencing neuron

A new review article, " Tonic NMDA Receptor Currents in the Brain: Regulation and Cognitive Functions, " has been published in Biological Psychiatry . The paper was co-corresponded by Wuhyun Koh and C. Justin Lee , and provides an updated perspective on tonic NMDA receptor currents in the brain. The article explores how neurotransmitters such as glutamate, glycine, and D-serine regulate tonic NMDA receptor activity, and how these mechanisms contribute to synaptic plasticity

On July 1, 2024 , we proudly launched the ABCD Lab (Astrocytes in Brain and Cognition Development Lab) , in Korean as “뇌 및 인지 발달에서의 별세포 기능 연구실.” Our mission is to uncover how astrocytes , the often-overlooked star-shaped glial cells, shape the foundations of brain development, cognition, and social behavior. By integrating approaches across disciplines, from molecular and cellular biology to systems neuroscience and behavioral analysis, the ABCD Lab seeks to advance our under